As a large contract research organization (CRO), CellCarta analyzes thousands of flow cytometry samples every month. CellCarta is leveraging automation tools such as CellEngine and laboratory information management systems (LIMS) for a seamless process.
This week at CYTO, we presented our poster examining the potential to identify cell types in CITE-seq data using hierarchical gating. Compared to clustering, gated populations have clear definitions based on specific marker expression levels. We compared cell type assignment by hierarchical gating vs. unbiased clustering.
No one is surprised to read that individuals coordinate their behavior and act as groups. We see collective behavior everywhere: from family gatherings, to corporate workplaces, and on the playing field. We also know that other animals act collectively. Birds flock, fish school, and wolf packs hunt. What might surprise us, however, is how ubiquitous the phenomenon is. Remarkably, coordinated, collective behavior can be seen in organisms as simple as bacteria, single-celled creatures without even a nucleus, much less a nervous system. Because they are so simple, bacteria can serve as a model organism for studying collective behavior. And because each individual is a single cell, CellEngine can be an important tool for analyzing that behavior.